
Denali Therapeutics (DNLI) Stock Forecast & Price Target
Denali Therapeutics (DNLI) Analyst Ratings
Bulls say
Denali Therapeutics Inc is well-positioned for growth, with management on track for an accelerated approval filing for its tivi BLA, which is expected to capture significant market share starting in 2026. The company has demonstrated synergies in in-house manufacturing, which is anticipated to support 1-2 Investigational New Drug (IND) applications annually through 2027, potentially enhancing the pipeline of Transport Vehicle (TV)-based programs. Positive clinical results, including improvements in liver volume and cognition rates, alongside careful monitoring of operating expenses that remain below estimates, contribute to a favorable outlook for Denali’s financial health and innovative product offerings.
Bears say
Denali Therapeutics Inc faces significant challenges that could hinder its future growth and profitability, particularly related to the delays and failures in the development and commercialization of its product candidates, which would likely negatively impact its business prospects. The company's discontinued III dose cohort for Elaprase raises concerns about real-world durability, potentially impairing the broader adoption of its gene therapy approaches and delaying revenue generation. Moreover, the challenges in achieving large-scale deployment of current Aß-MAbs, coupled with a reported net loss of $114.8 million, underscore critical financial vulnerabilities that may adversely affect the company’s market position and financial forecasts.
This aggregate rating is based on analysts' research of Denali Therapeutics and is not a guaranteed prediction by Public.com or investment advice.
Denali Therapeutics (DNLI) Analyst Forecast & Price Prediction
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