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KPTI
Volume: 34.85K
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Karyopharm Therapeutics (KPTI) Stock Forecast & Price Target

Karyopharm Therapeutics (KPTI) Analyst Ratings

Based on 17 analyst ratings
Buy
Strong Buy 29%
Buy 41%
Hold 24%
Sell 6%
Strong Sell 0%

Bulls say

Karyopharm Therapeutics Inc. presents a positive outlook due to its commercial product, XPOVIO (selinexor), which has demonstrated strong efficacy in treating multiple myeloma and has recently expanded its indications, suggesting significant revenue potential. Forecasts suggest that XPOVIO could achieve sales growth to around $500 million in out-years, supported by a steady revenue stream estimated at approximately $120 million annually over the next decade. Furthermore, the expected revenue for 2025 is projected to be in the range of $115 to $130 million, indicating an 11% year-over-year growth, underlining the company's favorable positioning in the market despite competitive pressures.

Bears say

Karyopharm Therapeutics faces significant challenges, primarily due to an increasingly crowded competitive landscape in the cancer treatment market, which may hinder the market uptake of its product, XPOVIO. Additionally, potential pipeline risks, including the failure to achieve FDA approval for selinexor in p53 wild-type endometrial cancer and the possibility of study failures in myelofibrosis (MF), further exacerbate the company's uncertain outlook. The fourth-quarter revenue of $30.5 million and an EPS of ($0.24) indicate that while the company has met estimates, underlying financial pressures such as increased 340B discounts and Medicare rebates negatively impacted product revenue in 2024, suggesting headwinds for future growth.

Karyopharm Therapeutics (KPTI) has been analyzed by 17 analysts, with a consensus rating of Buy. 29% of analysts recommend a Strong Buy, 41% recommend Buy, 24% suggest Holding, 6% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Karyopharm Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Karyopharm Therapeutics (KPTI) Forecast

Analysts have given Karyopharm Therapeutics (KPTI) a Buy based on their latest research and market trends.

According to 17 analysts, Karyopharm Therapeutics (KPTI) has a Buy consensus rating as of Jul 3, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $25.47, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $25.47, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Karyopharm Therapeutics (KPTI)

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